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Can Cannabinoids Help with Irritable Bowel Syndrome?

Our digestive systems can be a little unpredictable. Digestive issues can come with cramping, bloating, constipation, and more leaving you uncomfortable and desperate for a solution. While avoiding certain foods, exercising, and drinking lots of water can make a difference, sometimes you need more support – and you’re not alone.

What is Irritable Bowel Syndrome (IBS)?

Irritable bowel syndrome is a fairly common gastrointestinal disorder, typically involving the large intestine, and while it’s not life-threatening, it can be debilitating. With approximately 11.2% of people all over the world suffering from IBS, it’s a common issue that keeps many people from enjoying life to the fullest.

The direct cause of Irritable Bowel Syndrome is unknown, but there are several factors that may play a part. Here are a few:

  • Muscle contractions in the intestines that are either too strong or too weak
  • Overreaction of the nervous system
  • Infection
  • Stress 
  • Gut microbiome (or the bacteria that help break down your food in your digestive system)

Digestion and Cannabinoids

There have been quite a few studies conducted on digestive issues including IBS, their symptoms, and how CBD and CBG have been shown to alleviate symptoms. One study, in particular, found that in mice the endogenous cannabinoid system was involved with inflammation characteristic of IBS and Irritable Bowel Disorder (IBD), indicating that impacting the endocannabinoid system can provide therapeutic relief. Cannabinoids have been found to work closely with the endocannabinoid system giving the system the boost it may need. 

Other studies have shown that cannabinoids, especially CBD and CBG, have been shown to stop human colorectal carcinoma cells from producing and growing more cancer cells and that cannabinoids like CBG can act as an appetite stimulant.

CBD or CBG may be a therapeutic promise of relief for those with IBS, cancer, in need of appetite stimulation, or other digestive issues despite not yet having been evaluated or approved by the FDA as a treatment for them. 


RESET Bioscience uses pharmaceutical technology to produce our cannabinoid drops. In addition to our water-based CBD, RESET Balance, we have other water-based drops to help you power through your day. RESET Function CBG, the first uniquely water-based CBG drops with faster, better, proven efficacy is here to help you start each day with a boost for your digestive system. Our products are THC-Free*, non-GMO, zero calories, manufactured in the US, and designed for optimal absorption to keep you feeling great all day long! RESET’s water-based drops are more effective than other products because they provide you with up to four times the absorption of CBG in oils, vapes, and edibles. Plus, you can enjoy them alone, on the go, or add them to drinks throughout the day with the same proven efficacy.